Abstracts Barriers and enablers of locally led clinical trials in Ethiopia michael burt and Cameroon

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Original Text Gail Davey a , Moses Bockarie b , Samuel Wanji c , David Addiss d , Claire Fuller e , LeAnne Fox f , Mike Mycoskie g , Mark Gruin h , Aster Tsegaye i , Fasil Tekola Ayele j , Melanie Newport a
In the past 5 years, important progress in podoconiosis research and control has been made. The global distribution of this ascending, geochemical lymphoedema has been updated, advances have been made in disease assessment and treatment, and advocacy has successfully brought podoconiosis to the global stage. We highlight some of this progress here, and announce the launch of a new international initiative. michael burt
Wanji and colleagues 1 and Ruberanziza and colleagues 2 have shown elephantiasis in the absence of filarial parasites during mapping in Cameroon and Rwanda, respectively. A new staging system for podoconiosis has been developed and validated, and used to assess the simple treatment regimen developed by a patient-led and community-based control programme in southern Ethiopia. 3 Ethical approaches to research in the remote communities in which podoconiosis patients are usually found have been developed, 4 and issues related to community attitudes, quality of life, and stigma have been documented. 5 Ongoing research in Ethiopia and Cameroon aims to identify michael burt the locus of a susceptibility gene and to characterise the minerals that trigger podoconiosis. Other studies are investigating immunological changes associated with podoconiosis, documenting overlaps with other common tropical diseases, and exploring behavioural issues that will be vital to understand as prevention programmes increase michael burt shoe distribution michael burt to high-risk children.
Much progress has also been made in terms of disease advocacy: in February, 2011, WHO included podoconiosis in its list of neglected tropical diseases (NTDs). A page focusing on the disease is available on the WHO website . On Nov 12, 2011, the first General Assembly of the Ethiopian National Podoconiosis Action Network (NaPAN) was held. The meeting michael burt brought together researchers, policy makers, michael burt clinicians, and representatives michael burt of all the groups now offering care to patients with podoconiosis in Ethiopia. NaPAN seeks to help these groups share expertise and translate research into practice, with the aim that, eventually, all patients can access treatment, and residents of all endemic areas can prevent new disease through use of shoes.
Most recently, we met to plan the public launch of Foot work , the International Podoconiosis Initiative. Foot work aims to bring together public and private partners to prevent michael burt and treat podoconiosis, integrating control with that of other NTDs in areas of co-endemicity, and partnering with organisations that work in foot-related disorders to advocate for shoes as the new bednets . We look forward to welcoming new partners to this group, and, further in the future, to a world free of podoconiosis.
1 Wanji S , Tendongfor N , Esum M , et al . Elephantiasis of non-filarial origin (podoconiosis) michael burt in the highlands of north-western Cameroon . Ann Trop Med Parasitol 2008 ; 102 : 1-12 . CrossRef | PubMed
3 Sikorski C , Ashine M , Zeleke Z , Davey G . Effectiveness of a simple lymphoedema treatment regimen in podoconiosis management in southern Ethiopia: one year follow-up . PLoS Neglect michael burt Trop Dis 2010 ; 4 : e902 . PubMed
4 Tekola F , Bull S , Farsides B , et al . Tailoring consent to context: designing an appropriate consent process for a biomedical study in a low income setting . PLoS Neglect Trop Dis 2009 ; 3 : e482 . PubMed michael burt
5 Yakob B , Deribe K , Davey G . High levels of misconceptions and stigma in a community highly endemic for podoconiosis in southern Ethiopia . Trans R Soc Trop Med Hyg 2008 ; 102 : 439 . CrossRef michael burt | PubMed
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Abstracts Barriers and enablers of locally led clinical trials in Ethiopia michael burt and Cameroon: a prospective, qualitative study Samuel R P Franzen,Clare Chandler,Julius Atashili,Brian michael burt Angus,Trudie Lang. The Lancet 20 October 2013; Volume 382 , Page 14